AmiGO 2: Term Details for "MAP kinase kinase kinase kinase activity" (GO:0008349)

Accession: GO:0008349
Name: MAP kinase kinase kinase kinase activity
Ontology: molecular_function
Synonyms: MAP4K activity, MAPKKKK
Alternate IDs: None
Definition: Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli. Source: PMID:11790549, GOC:bf
Comment: None
History: See term history for GO:0008349 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to MAP kinase kinase kinase kinase activity (excluding "regulates").; Link to all direct and indirect annotations to MAP kinase kinase kinase kinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for MAP kinase kinase kinase kinase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
MAP kinase kinase kinase kinase activity	is_a	protein serine/threonine kinase activity (GO:0004674)
MAP kinase kinase kinase kinase activity	RO:0002162	Eukaryota (NCBITaxon:2759)
MAP kinase kinase kinase kinase activity	BFO:0000050	MAPK cascade (GO:0000165)

subject	relation	object
JUN kinase kinase kinase kinase activity (GO:0042656)	is_a	MAP kinase kinase kinase kinase activity