AmiGO 2: Term Details for "glycoprotein 6-alpha-L-fucosyltransferase activity" (GO:0008424)

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Term Information

Accession: GO:0008424
Name: glycoprotein 6-alpha-L-fucosyltransferase activity
Ontology: molecular_function
Synonyms: FucT, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity, GDP-L-fucose--glycoprotein fucosyltransferase activity, GDP-fucose--glycoprotein fucosyltransferase activity, GDPfucose-glycoprotein fucosyltransferase activity, guanosine diphosphofucose--glycoprotein fucosyltransferase activity, glycoprotein fucosyltransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+. Source: RHEA:12985, EC:2.4.1.68
Comment: None
History: See term history for GO:0008424 at QuickGO
Chem. react.: has participant GDP-beta-L-fucose(2-); has participant hydron; has participant GDP(3-); has participant N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-Asn residue; has participant N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue
Subset: None
Related: Link to all genes and gene products annotated to glycoprotein 6-alpha-L-fucosyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to glycoprotein 6-alpha-L-fucosyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for glycoprotein 6-alpha-L-fucosyltransferase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003824 catalytic activity
GO:0008150 biological_process
GO:0016740 transferase activity
GO:0016757 glycosyltransferase activity
GO:0008152 metabolic process
GO:0003674 molecular_function
GO:0070085 glycosylation
GO:0016758 hexosyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0036065 fucosylation
GO:0008417 fucosyltransferase activity
GO:0046921 alpha-(1->6)-fucosyltransferase activity
GO:0140103 catalytic activity, acting on a glycoprotein
GO:0036071 N-glycan fucosylation
GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity

Parents of glycoprotein 6-alpha-L-fucosyltransferase activity (GO:0008424)

subject	relation	object
glycoprotein 6-alpha-L-fucosyltransferase activity	is_a	catalytic activity, acting on a glycoprotein (GO:0140103)
glycoprotein 6-alpha-L-fucosyltransferase activity	is_a	alpha-(1->6)-fucosyltransferase activity (GO:0046921)
glycoprotein 6-alpha-L-fucosyltransferase activity	BFO:0000050	N-glycan fucosylation (GO:0036071)
glycoprotein 6-alpha-L-fucosyltransferase activity	RO:0000057	GDP-beta-L-fucose(2-) (CHEBI:57273)
glycoprotein 6-alpha-L-fucosyltransferase activity	RO:0000057	hydron (CHEBI:15378)
glycoprotein 6-alpha-L-fucosyltransferase activity	RO:0000057	GDP(3-) (CHEBI:58189)
glycoprotein 6-alpha-L-fucosyltransferase activity	RO:0000057	N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-Asn residue (CHEBI:137207)
glycoprotein 6-alpha-L-fucosyltransferase activity	RO:0000057	N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue (CHEBI:60651)

This term has no children.

EC: 2.4.1.68
KEGG_REACTION: R05988
MetaCyc: 2.4.1.68-RXN
Reactome: R-HSA-1028788; R-HSA-9696980
RHEA: 12985