AmiGO 2: Term Details for "GDP-mannose 4,6-dehydratase activity" (GO:0008446)

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Term Information

Accession: GO:0008446
Name: GDP-mannose 4,6-dehydratase activity
Ontology: molecular_function
Synonyms: GDP-D-mannose 4,6-dehydratase activity, GDP-D-mannose dehydratase activity, GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming), GDP-mannose 4,6-hydro-lyase activity, GDPmannose 4,6-dehydratase activity, Gmd, guanosine 5'-diphosphate-D-mannose oxidoreductase activity, guanosine diphosphomannose 4,6-dehydratase activity, guanosine diphosphomannose oxidoreductase activity
Alternate IDs: None
Definition: Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O. Source: RHEA:23820, EC:4.2.1.47
Comment: None
History: See term history for GO:0008446 at QuickGO
Chem. react.: has participant GDP-alpha-D-mannose(2-); has participant water; has participant GDP-4-dehydro-6-deoxy-alpha-D-mannose(2-)
Subset: None
Related: Link to all genes and gene products annotated to GDP-mannose 4,6-dehydratase activity (excluding "regulates").; Link to all direct and indirect annotations to GDP-mannose 4,6-dehydratase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for GDP-mannose 4,6-dehydratase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity
GO:0008446 GDP-mannose 4,6-dehydratase activity

Parents of GDP-mannose 4,6-dehydratase activity (GO:0008446)

subject	relation	object
GDP-mannose 4,6-dehydratase activity	is_a	hydro-lyase activity (GO:0016836)
GDP-mannose 4,6-dehydratase activity	RO:0000057	GDP-alpha-D-mannose(2-) (CHEBI:57527)
GDP-mannose 4,6-dehydratase activity	RO:0000057	water (CHEBI:15377)
GDP-mannose 4,6-dehydratase activity	RO:0000057	GDP-4-dehydro-6-deoxy-alpha-D-mannose(2-) (CHEBI:57964)

This term has no children.

EC: 4.2.1.47
KEGG_REACTION: R00888
MetaCyc: GDPMANDEHYDRA-RXN
Reactome: R-HSA-6787632
RHEA: 23820