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alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

Term Information

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Accession
GO:0008454
Name
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
Ontology
molecular_function
Synonyms
alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity, GnTIV activity, N-acetylglucosaminyltransferase IV activity, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity, UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity, alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity, beta-acetylglucosaminyltransferase IV activity, uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV
Alternate IDs
None
Definition
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R. Source: EC:2.4.1.145
Comment
None
History
See term history for GO:0008454 at QuickGO
Chem. react.
has participant N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue
has participant UDP(3-)
has participant N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue
has participant UDP-N-acetyl-alpha-D-glucosamine(2-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0008454 from QuickGO

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Parents of alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (GO:0008454)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [RO:0000057 relation] RO:0000057  N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue (CHEBI:139507)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [RO:0000057 relation] RO:0000057  UDP(3-) (CHEBI:58223)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [RO:0000057 relation] RO:0000057  N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue (CHEBI:60651)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [RO:0000057 relation] RO:0000057  UDP-N-acetyl-alpha-D-glucosamine(2-) (CHEBI:57705)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [is_a relation] is_a  acetylglucosaminyltransferase activity (GO:0008375)
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [is_a relation] is_a  catalytic activity, acting on a glycoprotein (GO:0140103)

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