AmiGO 2: Term Details for "folate:monoatomic anion antiporter activity" (GO:0008518)

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Term Information

Accession: GO:0008518
Name: folate:monoatomic anion antiporter activity
Ontology: molecular_function
Synonyms: reduced folate carrier activity, reduced folate transmembrane transporter activity, reduced folate transporter, folate:anion antiporter activity
Alternate IDs: None
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF. Source: GOC:mtg_transport, PMID:24745983, PMID:21568705, TC:2.A.48
Comment: None
History: See term history for GO:0008518 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to folate:monoatomic anion antiporter activity (excluding "regulates").; Link to all direct and indirect annotations to folate:monoatomic anion antiporter activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for folate:monoatomic anion antiporter activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0071702 organic substance transport
GO:0009987 cellular process
GO:0051234 establishment of localization
GO:0003674 molecular_function
GO:0015849 organic acid transport
GO:0015711 organic anion transport
GO:0055085 transmembrane transport
GO:0006810 transport
GO:0046942 carboxylic acid transport
GO:0006811 monoatomic ion transport
GO:0071705 nitrogen compound transport
GO:1903825 organic acid transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0005215 transporter activity
GO:0051180 vitamin transport
GO:0022804 active transmembrane transporter activity
GO:0042886 amide transport
GO:1905039 carboxylic acid transmembrane transport
GO:0006835 dicarboxylic acid transport
GO:0072337 modified amino acid transport
GO:0006820 monoatomic anion transport
GO:0034220 monoatomic ion transmembrane transport
GO:0005342 organic acid transmembrane transporter activity
GO:0008514 organic anion transmembrane transporter activity
GO:0035461 vitamin transmembrane transport
GO:0042887 amide transmembrane transporter activity
GO:0046943 carboxylic acid transmembrane transporter activity
GO:0015884 folic acid transport
GO:0072349 modified amino acid transmembrane transporter activity
GO:0098656 monoatomic anion transmembrane transport
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0015291 secondary active transmembrane transporter activity
GO:0090482 vitamin transmembrane transporter activity
GO:0022853 active monoatomic ion transmembrane transporter activity
GO:0015297 antiporter activity
GO:0008517 folic acid transmembrane transporter activity
GO:0008509 monoatomic anion transmembrane transporter activity
GO:0008518 folate:monoatomic anion antiporter activity

Parents of folate:monoatomic anion antiporter activity (GO:0008518)

subject	relation	object
folate:monoatomic anion antiporter activity	is_a	antiporter activity (GO:0015297)
folate:monoatomic anion antiporter activity	RO:0004009	folate(2-) (CHEBI:62501)
folate:monoatomic anion antiporter activity	is_a	active monoatomic ion transmembrane transporter activity (GO:0022853)
folate:monoatomic anion antiporter activity	is_a	folic acid transmembrane transporter activity (GO:0008517)
folate:monoatomic anion antiporter activity	RO:0004009	monoatomic anion (CHEBI:23905)
folate:monoatomic anion antiporter activity	is_a	monoatomic anion transmembrane transporter activity (GO:0008509)

This term has no children.

TC: 2.A.48