AmiGO 2: Term Details for "JUN kinase kinase activity" (GO:0008545)

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Term Information

Accession: GO:0008545
Name: JUN kinase kinase activity
Ontology: molecular_function
Synonyms: JNKK
Alternate IDs: None
Definition: Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. Source: PMID:11790549, GOC:bf, PMID:11057897
Comment: None
History: See term history for GO:0008545 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to JUN kinase kinase activity (excluding "regulates").; Link to all direct and indirect annotations to JUN kinase kinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for JUN kinase kinase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0003824 catalytic activity
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0003674 molecular_function
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0016740 transferase activity
GO:0005622 intracellular anatomical structure
GO:0007165 signal transduction
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0140096 catalytic activity, acting on a protein
GO:0035556 intracellular signal transduction
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0141124 intracellular signaling cassette
GO:0004672 protein kinase activity
GO:0000165 MAPK cascade
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0007254 JNK cascade
GO:0004708 MAP kinase kinase activity
GO:0008545 JUN kinase kinase activity

Parents of JUN kinase kinase activity (GO:0008545)

subject	relation	object
JUN kinase kinase activity	BFO:0000050	JNK cascade (GO:0007254)
JUN kinase kinase activity	is_a	MAP kinase kinase activity (GO:0004708)

This term has no children.

Reactome: R-HSA-168162