AmiGO 2: Term Details for "epsilon DNA polymerase complex" (GO:0008622)

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Term Information

Accession: GO:0008622
Name: epsilon DNA polymerase complex
Ontology: cellular_component
Synonyms: DNA polymerase epsilon complex
Alternate IDs: None
Definition: A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. Source: PMID:15814431, PMID:9745046
Comment: None
History: See term history for GO:0008622 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to epsilon DNA polymerase complex (excluding "regulates").; Link to all direct and indirect annotations to epsilon DNA polymerase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for epsilon DNA polymerase complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
GO:0008150 biological_process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0044237 cellular metabolic process
GO:0043170 macromolecule metabolic process
GO:0003674 molecular_function
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0003824 catalytic activity
GO:0044249 cellular biosynthetic process
GO:0005622 intracellular anatomical structure
GO:0031974 membrane-enclosed lumen
GO:0090304 nucleic acid metabolic process
GO:0043226 organelle
GO:1901362 organic cyclic compound biosynthetic process
GO:0032991 protein-containing complex
GO:0140640 catalytic activity, acting on a nucleic acid
GO:1902494 catalytic complex
GO:0006259 DNA metabolic process
GO:0043229 intracellular organelle
GO:0009059 macromolecule biosynthetic process
GO:0043227 membrane-bounded organelle
GO:0043228 non-membrane-bounded organelle
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0043233 organelle lumen
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0140097 catalytic activity, acting on DNA
GO:0071897 DNA biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043232 intracellular non-membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0016779 nucleotidyltransferase activity
GO:0005634 nucleus
PR:000050567 protein-containing material entity
GO:1990234 transferase complex
GO:0005694 chromosome
GO:0034061 DNA polymerase activity
GO:0140535 intracellular protein-containing complex
GO:0031981 nuclear lumen
GO:0061695 transferase complex, transferring phosphorus-containing groups
GO:0042575 DNA polymerase complex
GO:0000228 nuclear chromosome
GO:0140513 nuclear protein-containing complex
GO:0008622 epsilon DNA polymerase complex

Parents of epsilon DNA polymerase complex (GO:0008622)

subject	relation	object
epsilon DNA polymerase complex	is_a	DNA polymerase complex (GO:0042575)
epsilon DNA polymerase complex	BFO:0000050	nuclear chromosome (GO:0000228)
epsilon DNA polymerase complex	is_a	nuclear protein-containing complex (GO:0140513)

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