AmiGO 2: Term Details for "granzyme-mediated apoptotic signaling pathway" (GO:0008626)

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Term Information

Accession: GO:0008626
Name: granzyme-mediated apoptotic signaling pathway
Ontology: biological_process
Synonyms: apoptotic signaling pathway in response to granzyme, induction of apoptosis by granzyme
Alternate IDs: None
Definition: The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. Source: GOC:mtg_apoptosis, PMID:17158907
Comment: None
History: See term history for GO:0008626 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to granzyme-mediated apoptotic signaling pathway (excluding "regulates").; Link to all direct and indirect annotations to granzyme-mediated apoptotic signaling pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for granzyme-mediated apoptotic signaling pathway (excluding "regulates").

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0008219 cell death
GO:0051716 cellular response to stimulus
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0140507 granzyme-mediated programmed cell death signaling pathway
GO:0008626 granzyme-mediated apoptotic signaling pathway

Parents of granzyme-mediated apoptotic signaling pathway (GO:0008626)

subject	relation	object
granzyme-mediated apoptotic signaling pathway	is_a	granzyme-mediated programmed cell death signaling pathway (GO:0140507)
granzyme-mediated apoptotic signaling pathway	is_a	apoptotic signaling pathway (GO:0097190)

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