AmiGO 2: Term Details for "apoptotic mitochondrial changes" (GO:0008637)

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Term Information

Accession: GO:0008637
Name: apoptotic mitochondrial changes
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The morphological and physiological alterations undergone by mitochondria during apoptosis. Source: GOC:mah, GOC:mtg_apoptosis
Comment: This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it.
History: See term history for GO:0008637 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to apoptotic mitochondrial changes (excluding "regulates").; Link to all direct and indirect annotations to apoptotic mitochondrial changes (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for apoptotic mitochondrial changes (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
GO:0008219 cell death
GO:0016043 cellular component organization
GO:0006996 organelle organization
GO:0012501 programmed cell death
GO:0006915 apoptotic process
GO:0007005 mitochondrion organization
GO:0008637 apoptotic mitochondrial changes
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process
GO:0001836 release of cytochrome c from mitochondria
GO:0032976 release of matrix enzymes from mitochondria

Parents of apoptotic mitochondrial changes (GO:0008637)

subject	relation	object
apoptotic mitochondrial changes	RO:0002162	Opisthokonta (NCBITaxon:33154)
apoptotic mitochondrial changes	is_a	mitochondrion organization (GO:0007005)
apoptotic mitochondrial changes	BFO:0000050	apoptotic process (GO:0006915)

Children of apoptotic mitochondrial changes (GO:0008637)

subject	relation	object
release of matrix enzymes from mitochondria (GO:0032976)	is_a	apoptotic mitochondrial changes
mitochondrial fragmentation involved in apoptotic process (GO:0043653)	is_a	apoptotic mitochondrial changes
release of cytochrome c from mitochondria (GO:0001836)	is_a	apoptotic mitochondrial changes
regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108)	is_a	apoptotic mitochondrial changes

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