AmiGO 2: Term Details for "cholate 7-alpha-dehydrogenase activity" (GO:0008709)

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Term Information

Accession: GO:0008709
Name: cholate 7-alpha-dehydrogenase activity
Ontology: molecular_function
Synonyms: 7alpha-HSDH, 7-alpha-hydroxysteroid dehydrogenase activity, 7alpha-hydroxy steroid dehydrogenase activity, 7alpha-hydroxysteroid dehydrogenase activity, 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity
Alternate IDs: None
Definition: Catalysis of the reaction: cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H+ + NADH. Source: RHEA:19409, EC:1.1.1.159
Comment: None
History: See term history for GO:0008709 at QuickGO
Chem. react.: has participant NAD(1-); has participant hydron; has participant 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate; has participant NADH(2-); has participant cholate
Subset: None
Related: Link to all genes and gene products annotated to cholate 7-alpha-dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to cholate 7-alpha-dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cholate 7-alpha-dehydrogenase activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016229 steroid dehydrogenase activity
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0008709 cholate 7-alpha-dehydrogenase activity

Parents of cholate 7-alpha-dehydrogenase activity (GO:0008709)

subject	relation	object
cholate 7-alpha-dehydrogenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
cholate 7-alpha-dehydrogenase activity	RO:0000057	hydron (CHEBI:15378)
cholate 7-alpha-dehydrogenase activity	RO:0000057	3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate (CHEBI:11893)
cholate 7-alpha-dehydrogenase activity	is_a	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764)
cholate 7-alpha-dehydrogenase activity	RO:0000057	NADH(2-) (CHEBI:57945)
cholate 7-alpha-dehydrogenase activity	RO:0000057	cholate (CHEBI:29747)

This term has no children.

EC: 1.1.1.159
KEGG_REACTION: R02792
MetaCyc: 7-ALPHA-HYDROXYSTEROID-DEH-RXN
RHEA: 19409