AmiGO 2: Term Details for "N-acetylneuraminate lyase activity" (GO:0008747)

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Term Information

Accession: GO:0008747
Name: N-acetylneuraminate lyase activity
Ontology: molecular_function
Synonyms: N-acetylneuraminate aldolase activity, N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming), N-acetylneuraminate pyruvate-lyase activity, N-acetylneuraminic acid aldolase activity, N-acetylneuraminic acid lyase activity, N-acetylneuraminic aldolase activity, N-acetylneuraminic lyase activity, NALase activity, NANA lyase activity, NPL, acetylneuraminate lyase activity, acetylneuraminate pyruvate-lyase activity, neuraminate aldolase activity, neuraminic acid aldolase activity, neuraminic aldolase activity, sialate lyase activity, sialic acid aldolase activity, sialic aldolase activity
Alternate IDs: None
Definition: Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate. Source: EC:4.1.3.3, RHEA:23296
Comment: None
History: See term history for GO:0008747 at QuickGO
Chem. react.: has participant aceneuramate; has participant aldehydo-N-acetyl-D-mannosamine; has participant pyruvate
Subset: None
Related: Link to all genes and gene products annotated to N-acetylneuraminate lyase activity (excluding "regulates").; Link to all direct and indirect annotations to N-acetylneuraminate lyase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for N-acetylneuraminate lyase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016830 carbon-carbon lyase activity
GO:0016833 oxo-acid-lyase activity
GO:0008747 N-acetylneuraminate lyase activity

Parents of N-acetylneuraminate lyase activity (GO:0008747)

subject	relation	object
N-acetylneuraminate lyase activity	is_a	oxo-acid-lyase activity (GO:0016833)
N-acetylneuraminate lyase activity	RO:0000057	aceneuramate (CHEBI:173083)
N-acetylneuraminate lyase activity	RO:0000057	aldehydo-N-acetyl-D-mannosamine (CHEBI:17122)
N-acetylneuraminate lyase activity	RO:0000057	pyruvate (CHEBI:15361)

This term has no children.

EC: 4.1.3.3
KEGG_REACTION: R01811
MetaCyc: RXN0-7390
Reactome: R-HSA-4085217
RHEA: 23296