AmiGO 2: Term Details for "UDP-N-acetylmuramate-L-alanine ligase activity" (GO:0008763)

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Term Information

Accession: GO:0008763
Name: UDP-N-acetylmuramate-L-alanine ligase activity
Ontology: molecular_function
Synonyms: L-Ala ligase activity, L-alanine-adding enzyme activity, UDP-MurNAc:L-alanine ligase activity, UDP-N-acetylmuramate:L-alanine ligase (ADP-forming), UDP-N-acetylmuramoyl-L-alanine synthetase activity, UDP-N-acetylmuramoylalanine synthetase activity, UDP-N-acetylmuramyl:L-alanine ligase activity, UDP-acetylmuramyl-L-alanine synthetase activity, UDPMurNAc-L-alanine synthetase activity, alanine-adding enzyme activity, uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity, uridine diphosphate N-acetylmuramate:L-alanine ligase activity, uridine diphospho-N-acetylmuramoylalanine synthetase activity, uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity, MurC synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanine. Source: EC:6.3.2.8, RHEA:23372
Comment: None
History: See term history for GO:0008763 at QuickGO
Chem. react.: has participant L-alanine zwitterion; has participant hydron; has participant UDP-N-acetyl-alpha-D-muramate(3-); has participant ATP(4-); has participant UDP-N-acetyl-alpha-D-muramoyl-L-alaninate(3-); has participant ADP(3-); has participant hydrogenphosphate
Subset: None
Related: Link to all genes and gene products annotated to UDP-N-acetylmuramate-L-alanine ligase activity (excluding "regulates").; Link to all direct and indirect annotations to UDP-N-acetylmuramate-L-alanine ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for UDP-N-acetylmuramate-L-alanine ligase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0016881 acid-amino acid ligase activity
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity

Parents of UDP-N-acetylmuramate-L-alanine ligase activity (GO:0008763)

subject	relation	object
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	L-alanine zwitterion (CHEBI:57972)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	hydron (CHEBI:15378)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	UDP-N-acetyl-alpha-D-muramate(3-) (CHEBI:70757)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	UDP-N-acetyl-alpha-D-muramoyl-L-alaninate(3-) (CHEBI:83898)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	ADP(3-) (CHEBI:456216)
UDP-N-acetylmuramate-L-alanine ligase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
UDP-N-acetylmuramate-L-alanine ligase activity	is_a	acid-amino acid ligase activity (GO:0016881)

This term has no children.

EC: 6.3.2.8
KEGG_REACTION: R03193
MetaCyc: UDP-NACMUR-ALA-LIG-RXN
RHEA: 23372