AmiGO 2: Term Details for "UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity" (GO:0008765)

Term Information

Accession: GO:0008765
Name: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity
Ontology: molecular_function
Synonyms: MurE synthetase activity, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming), UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity, UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity, UDP-N-acetylmuramyl-tripeptide synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate. Source: EC:6.3.2.13, RHEA:23676
Comment: None
History: See term history for GO:0008765 at QuickGO
Chem. react.: has participant UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-); has participant ADP(3-); has participant hydrogenphosphate; has participant meso-2,6-diaminopimelic acid dizwitterion; has participant hydron; has participant UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-); has participant ATP(4-)
Subset: None
Related: Link to all genes and gene products annotated to UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (excluding "regulates").; Link to all direct and indirect annotations to UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0016881 acid-amino acid ligase activity
GO:0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity

Parents of UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (GO:0008765)

subject	relation	object
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-) (CHEBI:83900)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	ADP(3-) (CHEBI:456216)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	meso-2,6-diaminopimelic acid dizwitterion (CHEBI:57791)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	hydron (CHEBI:15378)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) (CHEBI:83905)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	is_a	acid-amino acid ligase activity (GO:0016881)
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)

This term has no children.

EC: 6.3.2.13
KEGG_REACTION: R02788
MetaCyc: UDP-NACMURALGLDAPLIG-RXN
RHEA: 23676