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UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity

Term Information

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Accession
GO:0008766
Name
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine. Source: RHEA:28374
Comment
Note that EC:6.3.2.15 was deleted from EC as the reaction is performed by UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (EC:6.3.2.10).
History
See term history for GO:0008766 at QuickGO
Chem. react.
has participant hydron
has participant UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-)
has participant hydrogenphosphate
has participant ATP(4-)
has participant D-alanyl-D-alanine zwitterion
has participant ADP(3-)
has participant UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alaninate(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0008766 from QuickGO

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Parents of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) (CHEBI:83905)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  D-alanyl-D-alanine zwitterion (CHEBI:57822)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [is_a relation] is_a  acid-amino acid ligase activity (GO:0016881)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  ADP(3-) (CHEBI:456216)
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity [RO:0000057 relation] RO:0000057  UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alaninate(4-) (CHEBI:61386)

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