Term Information

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Accession
GO:0008794
Name
arsenate reductase (glutaredoxin) activity
Ontology
molecular_function
Synonyms
glutharedoxin:arsenate oxidoreductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione. Source: EC:1.20.4.1, PMID:10593884, GOC:kd
Comment
None
History
See term history for GO:0008794 at QuickGO
Chem. react.
has participant arsenite(1-)
has participant water
has participant glutathionate(1-)
has participant S-(S-glutathionyl)-L-cysteine(1-) residue
has participant arsenate(2-)
has participant L-cysteine residue
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0008794 from QuickGO

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Parents of arsenate reductase (glutaredoxin) activity (GO:0008794)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  arsenite(1-) (CHEBI:29242)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  glutathionate(1-) (CHEBI:57925)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  S-(S-glutathionyl)-L-cysteine(1-) residue (CHEBI:146199)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  arsenate(2-) (CHEBI:48597)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  L-cysteine residue (CHEBI:29950)
arsenate reductase (glutaredoxin) activity [is_a relation] is_a  oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor (GO:0030614)
arsenate reductase (glutaredoxin) activity [is_a relation] is_a  arsenate reductase activity (GO:0030611)
arsenate reductase (glutaredoxin) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
1.20.4.1
MetaCyc
RXN-982
RHEA
22016
UM-BBD_reactionID
r0635