AmiGO 2: Term Details for "beta-lactamase activity" (GO:0008800)

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Term Information

Accession: GO:0008800
Name: beta-lactamase activity
Ontology: molecular_function
Synonyms: ampicillinase activity, beta-lactam hydrolase activity, beta-lactamase A, B, C, beta-lactamase AME I, beta-lactamase I-III, cephalosporin-beta-lactamase activity, exopenicillinase activity, neutrapen, penicillin amido-beta-lactamhydrolase activity, penicillin beta-lactamase activity, penicillinase I, II
Alternate IDs: None
Definition: Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. Source: EC:3.5.2.6
Comment: None
History: See term history for GO:0008800 at QuickGO
Chem. react.: has participant substituted beta-amino acid zwitterion; has participant beta-lactam; has participant water
Subset: None
Related: Link to all genes and gene products annotated to beta-lactamase activity (excluding "regulates").; Link to all direct and indirect annotations to beta-lactamase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for beta-lactamase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0008800 beta-lactamase activity
GO:0033251 cephalosporinase activity
GO:0033250 penicillinase activity
GO:0033252 regulation of beta-lactamase activity

Parents of beta-lactamase activity (GO:0008800)

subject	relation	object
beta-lactamase activity	RO:0000057	substituted beta-amino acid zwitterion (CHEBI:140347)
beta-lactamase activity	RO:0000057	beta-lactam (CHEBI:35627)
beta-lactamase activity	RO:0000057	water (CHEBI:15377)
beta-lactamase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (GO:0016812)

Children of beta-lactamase activity (GO:0008800)

subject	relation	object
cephalosporinase activity (GO:0033251)	is_a	beta-lactamase activity
penicillinase activity (GO:0033250)	is_a	beta-lactamase activity
regulation of beta-lactamase activity (GO:0033252)	RO:0002211	beta-lactamase activity

EC: 3.5.2.6
MetaCyc: BETA-LACTAMASE-RXN
RHEA: 20401