Term Information

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Accession
GO:0008840
Name
4-hydroxy-tetrahydrodipicolinate synthase activity
Ontology
molecular_function
Synonyms
dihydrodipicolinate synthase activity, DHDPS activity, L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing), L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming], dihydrodipicolinate synthetase activity, dihydrodipicolinic acid synthase activity
Alternate IDs
None
Definition
Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O. Source: RHEA:34171, PMID:8993314
Comment
None
History
See term history for GO:0008840 at QuickGO
Chem. react.
has participant water
has participant hydron
has participant L-aspartic acid 4-semialdehyde zwitterion
has participant pyruvate
has participant (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 4-hydroxy-tetrahydrodipicolinate synthase activity (GO:0008840)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
4-hydroxy-tetrahydrodipicolinate synthase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
4-hydroxy-tetrahydrodipicolinate synthase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
4-hydroxy-tetrahydrodipicolinate synthase activity [RO:0000057 relation] RO:0000057  L-aspartic acid 4-semialdehyde zwitterion (CHEBI:537519)
4-hydroxy-tetrahydrodipicolinate synthase activity [RO:0000057 relation] RO:0000057  pyruvate (CHEBI:15361)
4-hydroxy-tetrahydrodipicolinate synthase activity [is_a relation] is_a  hydro-lyase activity (GO:0016836)
4-hydroxy-tetrahydrodipicolinate synthase activity [RO:0000057 relation] RO:0000057  (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate(2-) (CHEBI:67139)

This term has no children.

EC
4.3.3.7
KEGG_REACTION
R02292
MetaCyc
DIHYDRODIPICSYN-RXN
RHEA
34171