AmiGO 2: Term Details for "glutamyl-tRNA reductase activity" (GO:0008883)

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Term Information

Accession: GO:0008883
Name: glutamyl-tRNA reductase activity
Ontology: molecular_function
Synonyms: L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)
Alternate IDs: None
Definition: Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H+ + NADPH. Source: EC:1.2.1.70, RHEA:12344
Comment: None
History: See term history for GO:0008883 at QuickGO
Chem. react.: has participant hydron; has participant NADPH(4-); has participant AMP 3'-end(1-) residue; has participant NADP(3-); has participant (S)-4-amino-5-oxopentanoic acid zwitterion; has participant 3'-(L-glutamate)adenylyl(1-) group
Subset: None
Related: Link to all genes and gene products annotated to glutamyl-tRNA reductase activity (excluding "regulates").; Link to all direct and indirect annotations to glutamyl-tRNA reductase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for glutamyl-tRNA reductase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016491 oxidoreductase activity
GO:0140098 catalytic activity, acting on RNA
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
GO:0140101 catalytic activity, acting on a tRNA
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0008883 glutamyl-tRNA reductase activity

Parents of glutamyl-tRNA reductase activity (GO:0008883)

subject	relation	object
glutamyl-tRNA reductase activity	RO:0000057	hydron (CHEBI:15378)
glutamyl-tRNA reductase activity	is_a	catalytic activity, acting on a tRNA (GO:0140101)
glutamyl-tRNA reductase activity	is_a	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620)
glutamyl-tRNA reductase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
glutamyl-tRNA reductase activity	RO:0000057	AMP 3'-end(1-) residue (CHEBI:78442)
glutamyl-tRNA reductase activity	RO:0000057	NADP(3-) (CHEBI:58349)
glutamyl-tRNA reductase activity	RO:0000057	(S)-4-amino-5-oxopentanoic acid zwitterion (CHEBI:57501)
glutamyl-tRNA reductase activity	RO:0000057	3'-(L-glutamate)adenylyl(1-) group (CHEBI:78520)

This term has no children.

EC: 1.2.1.70
KEGG_REACTION: R04109
MetaCyc: GLUTRNAREDUCT-RXN
RHEA: 12344