AmiGO 2: Term Details for "glutathionylspermidine synthase activity" (GO:0008885)

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Term Information

Accession: GO:0008885
Name: glutathionylspermidine synthase activity
Ontology: molecular_function
Synonyms: GSP synthetase activity, gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule], gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity, glutathione:spermidine ligase (ADP-forming) activity, glutathionylspermidine synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate. Source: EC:6.3.1.8
Comment: None
History: See term history for GO:0008885 at QuickGO
Chem. react.: has participant glutathionate(1-); has participant ADP(3-); has participant hydron; has participant hydrogenphosphate; has participant spermidine(3+); has participant ATP(4-); has participant glutathionylspermidinium(2+)
Subset: None
Related: Link to all genes and gene products annotated to glutathionylspermidine synthase activity (excluding "regulates").; Link to all direct and indirect annotations to glutathionylspermidine synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for glutathionylspermidine synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0016880 acid-ammonia (or amide) ligase activity
GO:0008885 glutathionylspermidine synthase activity

Parents of glutathionylspermidine synthase activity (GO:0008885)

subject	relation	object
glutathionylspermidine synthase activity	RO:0000057	glutathionate(1-) (CHEBI:57925)
glutathionylspermidine synthase activity	RO:0000057	ADP(3-) (CHEBI:456216)
glutathionylspermidine synthase activity	RO:0000057	hydron (CHEBI:15378)
glutathionylspermidine synthase activity	is_a	acid-ammonia (or amide) ligase activity (GO:0016880)
glutathionylspermidine synthase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
glutathionylspermidine synthase activity	RO:0000057	spermidine(3+) (CHEBI:57834)
glutathionylspermidine synthase activity	RO:0000057	ATP(4-) (CHEBI:30616)
glutathionylspermidine synthase activity	RO:0000057	glutathionylspermidinium(2+) (CHEBI:57835)

This term has no children.

EC: 6.3.1.8
MetaCyc: GSPSYN-RXN
RHEA: 21272