AmiGO 2: Term Details for "holo-[acyl-carrier-protein] synthase activity" (GO:0008897)

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Term Information

Accession: GO:0008897
Name: holo-[acyl-carrier-protein] synthase activity
Ontology: molecular_function
Synonyms: 4'-phosphopantetheinyltransferase activity, alpha-aminoadipate reductase phosphopantetheinyl transferase activity, phosphopantetheinyltransferase activity, 4'-phosphopantetheinyl transferase activity, ACPS activity, AcpS, CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity, CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity, P-pant transferase activity, PPTase activity, acyl carrier protein holoprotein (holo-ACP) synthetase activity, acyl carrier protein synthase activity, acyl carrier protein synthetase activity, alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity, alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity, coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity, holo-ACP synthase activity, holo-ACP synthetase activity, holo-acyl-carrier-protein synthase activity, holosynthase activity, phosphopantetheinyl transferase, L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity, holo-[peptidyl-carrier protein] synthase activity
Alternate IDs: GO:0008958
Definition: Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. Source: PMID:11867633, EC:2.7.8.7, PMID:10320345, PMID:8939709
Comment: None
History: See term history for GO:0008897 at QuickGO
Chem. react.: has participant L-serine residue; has participant O-(pantetheine-4'-phosphoryl)serine(1-) residue; has participant adenosine 3',5'-bismonophosphate(4-); has participant hydron; has participant coenzyme A(4-)
Subset: None
Related: Link to all genes and gene products annotated to holo-[acyl-carrier-protein] synthase activity (excluding "regulates").; Link to all direct and indirect annotations to holo-[acyl-carrier-protein] synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for holo-[acyl-carrier-protein] synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0008897 holo-[acyl-carrier-protein] synthase activity

Parents of holo-[acyl-carrier-protein] synthase activity (GO:0008897)

subject	relation	object
holo-[acyl-carrier-protein] synthase activity	RO:0000057	L-serine residue (CHEBI:29999)
holo-[acyl-carrier-protein] synthase activity	is_a	phosphotransferase activity, for other substituted phosphate groups (GO:0016780)
holo-[acyl-carrier-protein] synthase activity	RO:0000057	O-(pantetheine-4'-phosphoryl)serine(1-) residue (CHEBI:64479)
holo-[acyl-carrier-protein] synthase activity	RO:0000057	adenosine 3',5'-bismonophosphate(4-) (CHEBI:58343)
holo-[acyl-carrier-protein] synthase activity	RO:0000057	hydron (CHEBI:15378)
holo-[acyl-carrier-protein] synthase activity	RO:0000057	coenzyme A(4-) (CHEBI:57287)

This term has no children.

EC: 2.7.8.7
MetaCyc: HOLO-ACP-SYNTH-RXN
Reactome: R-HSA-199202
RHEA: 12068