Term Information

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Accession
GO:0008922
Name
long-chain fatty acid [acyl-carrier-protein] ligase activity
Ontology
molecular_function
Synonyms
acyl-ACP synthetase activity, long-chain fatty acid-[acyl-carrier-protein] ligase activity, long-chain-fatty-acid-ACP ligase activity, long-chain-fatty-acid-[acyl-carrier protein] ligase activity, long-chain-fatty-acid-[acyl-carrier-protein] ligase activity, acyl-[acyl-carrier-protein] synthetase activity, acyl-acyl-carrier-protein synthetase activity, acyl-acyl-carrier-proteinsynthetase activity, long-chain-fatty-acid-acyl-carrier-protein ligase activity, long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity, stearoyl-ACP synthetase activity, acyl-acyl carrier protein synthetase
Alternate IDs
GO:0010300
Definition
Catalysis of the reaction: a long-chain fatty acid + ATP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. Source: EC:6.2.1.20
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History
See term history for GO:0008922 at QuickGO
Chem. react.
has participant O-(pantetheine-4'-phosphoryl)serine(1-) residue
has participant adenosine 5'-monophosphate(2-)
has participant long-chain fatty acid anion
has participant diphosphate(3-)
has participant ATP(4-)
has participant O-[S-(long-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0008922 from QuickGO

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Parents of long-chain fatty acid [acyl-carrier-protein] ligase activity (GO:0008922)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  O-(pantetheine-4'-phosphoryl)serine(1-) residue (CHEBI:64479)
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  long-chain fatty acid anion (CHEBI:57560)
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
long-chain fatty acid [acyl-carrier-protein] ligase activity [RO:0000057 relation] RO:0000057  O-[S-(long-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue (CHEBI:133243)
long-chain fatty acid [acyl-carrier-protein] ligase activity [is_a relation] is_a  fatty acid ligase activity (GO:0015645)

This term has no children.

EC
6.2.1.20
KEGG_REACTION
R07325
MetaCyc
ACYLACPSYNTH-RXN
RHEA
45588