Term Information

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Accession
GO:0009022
Name
tRNA nucleotidyltransferase activity
Ontology
molecular_function
Synonyms
RNase PH activity, phosphate-dependent exonuclease activity, ribonuclease PH activity
Alternate IDs
None
Definition
Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. Source: PMID:2455297, RHEA:10628
Comment
Note that, although EC names the enzme tRNA nucleotidyltransferase, the enzyme to which this term refers is also known as 'ribonuclease PH', and degrades tRNA in the 3'-5' direction in vivo, the term does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis It should not be confused with CCA tRNA nucleotidyltransferase..
History
See term history for GO:0009022 at QuickGO
Chem. react.
has participant nucleoside 5'-diphosphate(3-)
has participant hydrogenphosphate
has participant tRNA 5'-phosphate polyanion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0009022 from QuickGO

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Parents of tRNA nucleotidyltransferase activity (GO:0009022)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tRNA nucleotidyltransferase activity [RO:0000057 relation] RO:0000057  nucleoside 5'-diphosphate(3-) (CHEBI:57930)
tRNA nucleotidyltransferase activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
tRNA nucleotidyltransferase activity [is_a relation] is_a  nucleotidyltransferase activity (GO:0016779)
tRNA nucleotidyltransferase activity [is_a relation] is_a  catalytic activity, acting on a tRNA (GO:0140101)
tRNA nucleotidyltransferase activity [RO:0000057 relation] RO:0000057  tRNA 5'-phosphate polyanion (CHEBI:173114)

This term has no children.