Term Information

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Accession
GO:0009035
Name
type I site-specific deoxyribonuclease activity
Ontology
molecular_function
Synonyms
type I restriction enzyme activity, ATP-dependent DNase activity, adenosine triphosphate-dependent deoxyribonuclease activity, deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent), deoxyribonuclease (adenosine triphosphate-hydrolyzing)
Alternate IDs
None
Definition
Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. Source: PMID:15788748, PMID:15300241
Comment
None
History
See term history for GO:0009035 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0009035 from QuickGO

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Parents of type I site-specific deoxyribonuclease activity (GO:0009035)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
type I site-specific deoxyribonuclease activity [is_a relation] is_a  restriction endodeoxyribonuclease activity (GO:0015666)
type I site-specific deoxyribonuclease activity [is_a relation] is_a  DNA translocase activity (GO:0015616)
type I site-specific deoxyribonuclease activity [is_a relation] is_a  endodeoxyribonuclease activity, producing 5'-phosphomonoesters (GO:0016888)
Children of type I site-specific deoxyribonuclease activity (GO:0009035)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
type I site-specific deoxyribonuclease complex (GO:0019812) [RO:0002215 relation] RO:0002215  type I site-specific deoxyribonuclease activity
negative regulation of type I site-specific deoxyribonuclease activity (GO:0032080) [RO:0002212 relation] RO:0002212  type I site-specific deoxyribonuclease activity
regulation of type I site-specific deoxyribonuclease activity (GO:0032084) [RO:0002211 relation] RO:0002211  type I site-specific deoxyribonuclease activity
EC
3.1.21.3
MetaCyc
3.1.21.3-RXN