AmiGO 2: Term Details for "excinuclease repair complex" (GO:0009380)

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Term Information

Accession: GO:0009380
Name: excinuclease repair complex
Ontology: cellular_component
Synonyms: UvrABC excinuclease complex, excinuclease ABC complex
Alternate IDs: None
Definition: Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap. Source: PMID:12145219, GOC:mah, GOC:mlg, PMID:15192705
Comment: None
History: See term history for GO:0009380 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to excinuclease repair complex (excluding "regulates").; Link to all direct and indirect annotations to excinuclease repair complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for excinuclease repair complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0003824 catalytic activity
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0009987 cellular process
GO:0016787 hydrolase activity
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0050896 response to stimulus
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0051716 cellular response to stimulus
GO:0016788 hydrolase activity, acting on ester bonds
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006950 response to stress
GO:0140097 catalytic activity, acting on DNA
GO:0033554 cellular response to stress
GO:0005575 cellular_component
GO:0006259 DNA metabolic process
GO:0003674 molecular_function
GO:0004518 nuclease activity
GO:0090304 nucleic acid metabolic process
GO:0032991 protein-containing complex
PR:000050567 protein-containing material entity
GO:1902494 catalytic complex
GO:0006974 DNA damage response
GO:0004536 DNA nuclease activity
GO:0004519 endonuclease activity
GO:0140535 intracellular protein-containing complex
GO:0004520 DNA endonuclease activity
GO:0006281 DNA repair
GO:1905348 endonuclease complex
GO:1990391 DNA repair complex
GO:1905347 endodeoxyribonuclease complex
GO:0009381 excinuclease ABC activity
GO:0009380 excinuclease repair complex

Parents of excinuclease repair complex (GO:0009380)

subject	relation	object
excinuclease repair complex	is_a	endodeoxyribonuclease complex (GO:1905347)
excinuclease repair complex	RO:0002215	excinuclease ABC activity (GO:0009381)
excinuclease repair complex	RO:0002216	DNA repair (GO:0006281)
excinuclease repair complex	is_a	DNA repair complex (GO:1990391)

This term has no children.