AmiGO 2: Term Details for "establishment of endothelial blood-brain barrier" (GO:0014045)

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Term Information

Accession: GO:0014045
Name: establishment of endothelial blood-brain barrier
Ontology: biological_process
Synonyms: establishment of endothelial BBB, establishment of endothelial blood/brain barrier
Alternate IDs: None
Definition: Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. Source: GOC:dph, PMID:20080302, GOC:sart, GOC:aruk, GOC:dgh, PMID:30280653
Comment: None
History: See term history for GO:0014045 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to establishment of endothelial blood-brain barrier (excluding "regulates").; Link to all direct and indirect annotations to establishment of endothelial blood-brain barrier (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for establishment of endothelial blood-brain barrier (excluding "regulates").

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GO:0048856 anatomical structure development
GO:0008150 biological_process
GO:0009888 tissue development
GO:0030154 cell differentiation
GO:0060429 epithelium development
GO:0032501 multicellular organismal process
GO:0048468 cell development
GO:0048869 cellular developmental process
GO:0009987 cellular process
GO:0032502 developmental process
GO:0003158 endothelium development
GO:0030855 epithelial cell differentiation
GO:0007275 multicellular organism development
GO:0048731 system development
GO:0045446 endothelial cell differentiation
GO:0002064 epithelial cell development
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0001885 endothelial cell development
GO:0060856 establishment of blood-brain barrier
GO:0061028 establishment of endothelial barrier
GO:0014045 establishment of endothelial blood-brain barrier

Parents of establishment of endothelial blood-brain barrier (GO:0014045)

subject	relation	object
establishment of endothelial blood-brain barrier	is_a	establishment of endothelial barrier (GO:0061028)
establishment of endothelial blood-brain barrier	is_a	establishment of blood-brain barrier (GO:0060856)

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