AmiGO 2: Term Details for "response to fluoxetine" (GO:0014076)

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Term Information

Accession: GO:0014076
Name: response to fluoxetine
Ontology: biological_process
Synonyms: response to SSRI, response to selective serotonin reuptake inhibitor
Alternate IDs: None
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. Source: GOC:pr, GOC:ef
Comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.
History: See term history for GO:0014076 at QuickGO
Chem. react.: None
Subset: gocheck_do_not_annotate
Related: Link to all genes and gene products annotated to response to fluoxetine (excluding "regulates").; Link to all direct and indirect annotations to response to fluoxetine (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for response to fluoxetine (excluding "regulates").

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GO:0008150 biological_process
GO:0050896 response to stimulus
GO:0042221 response to chemical
GO:0036276 response to antidepressant
GO:0014076 response to fluoxetine
GO:0071411 cellular response to fluoxetine

Parents of response to fluoxetine (GO:0014076)

subject	relation	object
response to fluoxetine	is_a	response to antidepressant (GO:0036276)
response to fluoxetine	RO:0004009	fluoxetine (CHEBI:5118)

Children of response to fluoxetine (GO:0014076)

subject	relation	object
cellular response to fluoxetine (GO:0071411)	is_a	response to fluoxetine

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