AmiGO 2: Term Details for "linoleoyl-CoA desaturase activity" (GO:0016213)

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Term Information

Accession: GO:0016213
Name: linoleoyl-CoA desaturase activity
Ontology: molecular_function
Synonyms: linoleoyl CoA desaturase activity, linoleoyl-coenzyme A desaturase activity, delta6-acyl CoA desaturase activity, delta6-desaturase activity, delta6-fatty acyl-CoA desaturase activity, fatty acid delta6-desaturase activity, linoleate desaturase activity, linoleic acid desaturase activity, linoleic desaturase activity, long-chain fatty acid delta6-desaturase activity, delta(6)-acyl CoA desaturase activity, delta(6)-desaturase activity, delta(6)-fatty acyl-CoA desaturase activity, fatty acid 6-desaturase activity, fatty acid delta(6)-desaturase activity, long-chain fatty acid delta(6)-desaturase activity
Alternate IDs: None
Definition: Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA). Source: PMID:7212717, RHEA:47140, RHEA:47144, PMID:12713571
Comment: Note that this function was formerly EC:1.14.99.25.
History: See term history for GO:0016213 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to linoleoyl-CoA desaturase activity (excluding "regulates").; Link to all direct and indirect annotations to linoleoyl-CoA desaturase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for linoleoyl-CoA desaturase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0016215 acyl-CoA desaturase activity
GO:0016213 linoleoyl-CoA desaturase activity

Parents of linoleoyl-CoA desaturase activity (GO:0016213)

subject	relation	object
linoleoyl-CoA desaturase activity	is_a	acyl-CoA desaturase activity (GO:0016215)

This term has no children.

EC: 1.14.19.3
MetaCyc: 1.14.19.3-RXN
Reactome: R-HSA-2046097; R-HSA-2046099; R-HSA-2046096; R-HSA-2046084
RHEA: 47140; 47144