AmiGO 2: Term Details for "prefoldin complex" (GO:0016272)

Accession: GO:0016272
Name: prefoldin complex
Ontology: cellular_component
Synonyms: GIM complex
Alternate IDs: None
Definition: A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. Source: PMID:9630229, GOC:jl, PMID:17384227, PMID:24068951
Comment: None
History: See term history for GO:0016272 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to prefoldin complex (excluding "regulates").; Link to all direct and indirect annotations to prefoldin complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for prefoldin complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
prefoldin complex	is_a	protein-containing complex (GO:0032991)

This term has no children.