AmiGO 2: Term Details for "1-phosphatidylinositol-3-kinase activity" (GO:0016303)

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Term Information

Accession: GO:0016303
Name: 1-phosphatidylinositol-3-kinase activity
Ontology: molecular_function
Synonyms: 1-phosphatidylinositol 3-kinase activity, PI3-kinase activity, PI3K, PtdIns-3-kinase activity, phosphatidylinositol 3-kinase activity, class I, phosphatidylinositol 3-kinase activity, class II, phosphatidylinositol 3-kinase activity, class III, phosphatidylinositol 3-kinase, class I, catalyst activity, type I phosphatidylinositol kinase activity, type III phosphoinositide 3-kinase activity
Alternate IDs: GO:0004429
Definition: Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+. Source: RHEA:12709, EC:2.7.1.137
Comment: None
History: See term history for GO:0016303 at QuickGO
Chem. react.: has participant hydron; has participant 1-phosphatidyl-1D-myo-inositol(1-); has participant ADP(3-); has participant ATP(4-); has participant 1-phosphatidyl-1D-myo-inositol 3-phosphate(3-)
Subset: None
Related: Link to all genes and gene products annotated to 1-phosphatidylinositol-3-kinase activity (excluding "regulates").; Link to all direct and indirect annotations to 1-phosphatidylinositol-3-kinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 1-phosphatidylinositol-3-kinase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0006793 phosphorus metabolic process
GO:0044238 primary metabolic process
GO:0009058 biosynthetic process
GO:0006629 lipid metabolic process
GO:0019637 organophosphate metabolic process
GO:0006796 phosphate-containing compound metabolic process
GO:0046486 glycerolipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0003674 molecular_function
GO:0090407 organophosphate biosynthetic process
GO:0006644 phospholipid metabolic process
GO:0003824 catalytic activity
GO:0045017 glycerolipid biosynthetic process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0046488 phosphatidylinositol metabolic process
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016301 kinase activity
GO:0006661 phosphatidylinositol biosynthetic process
GO:0001727 lipid kinase activity
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0052742 phosphatidylinositol kinase activity
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0005942 phosphatidylinositol 3-kinase complex

Parents of 1-phosphatidylinositol-3-kinase activity (GO:0016303)

subject	relation	object
1-phosphatidylinositol-3-kinase activity	BFO:0000050	phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)
1-phosphatidylinositol-3-kinase activity	RO:0000057	hydron (CHEBI:15378)
1-phosphatidylinositol-3-kinase activity	RO:0000057	1-phosphatidyl-1D-myo-inositol(1-) (CHEBI:57880)
1-phosphatidylinositol-3-kinase activity	RO:0000057	ADP(3-) (CHEBI:456216)
1-phosphatidylinositol-3-kinase activity	RO:0000057	ATP(4-) (CHEBI:30616)
1-phosphatidylinositol-3-kinase activity	is_a	phosphatidylinositol kinase activity (GO:0052742)
1-phosphatidylinositol-3-kinase activity	RO:0000057	1-phosphatidyl-1D-myo-inositol 3-phosphate(3-) (CHEBI:58088)

Children of 1-phosphatidylinositol-3-kinase activity (GO:0016303)

subject	relation	object
phosphatidylinositol 3-kinase complex (GO:0005942)	RO:0002215	1-phosphatidylinositol-3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity (GO:0046935)	RO:0002578	1-phosphatidylinositol-3-kinase activity

EC: 2.7.1.137
KEGG_REACTION: R03362
MetaCyc: 1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN
Reactome: R-HSA-9680389; R-HSA-9670433; R-HSA-109699; R-HSA-2045911; R-HSA-1675939; R-HSA-1676024; R-HSA-6798174; R-HSA-1675961; R-HSA-5672012; R-HSA-1433514
RHEA: 12709