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15-hydroxyprostaglandin dehydrogenase (NAD+) activity

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Accession
GO:0016404
Name
15-hydroxyprostaglandin dehydrogenase (NAD+) activity
Ontology
molecular_function
Synonyms
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity, 11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity, 15-OH-PGDH, 15-hydroxyprostaglandin dehydrogenase activity, 15-hydroxyprostanoic dehydrogenase activity, NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I), NAD-specific 15-hydroxyprostaglandin dehydrogenase activity, prostaglandin dehydrogenase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. Source: EC:1.1.1.141
Comment
None
History
See term history for GO:0016404 at QuickGO
Chem. react.
has participant prostaglandin E2(1-)
has participant hydron
has participant NADH(2-)
has participant NAD(1-)
has participant 15-dehydro-prostaglandin E2(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 15-hydroxyprostaglandin dehydrogenase (NAD+) activity (GO:0016404)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [RO:0000057 relation] RO:0000057  prostaglandin E2(1-) (CHEBI:606564)
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [RO:0000057 relation] RO:0000057  NADH(2-) (CHEBI:57945)
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [RO:0000057 relation] RO:0000057  15-dehydro-prostaglandin E2(1-) (CHEBI:57400)
15-hydroxyprostaglandin dehydrogenase (NAD+) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

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