AmiGO 2: Term Details for "long-chain-3-hydroxyacyl-CoA dehydrogenase activity" (GO:0016509)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0016509
Name: long-chain-3-hydroxyacyl-CoA dehydrogenase activity
Ontology: molecular_function
Synonyms: LCHAD, beta-hydroxyacyl-CoA dehydrogenase activity, long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity, long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity
Alternate IDs: None
Definition: Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. Source: EC:1.1.1.211, GOC:pde, RHEA:52656
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History: See term history for GO:0016509 at QuickGO
Chem. react.: has participant hydron; has participant NAD(1-); has participant long-chain 3-oxo-fatty acyl-CoA(4-); has participant long-chain (3S)-hydroxy fatty acyl-CoA(4-); has participant NADH(2-)
Subset: None
Related: Link to all genes and gene products annotated to long-chain-3-hydroxyacyl-CoA dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to long-chain-3-hydroxyacyl-CoA dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for long-chain-3-hydroxyacyl-CoA dehydrogenase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity

Parents of long-chain-3-hydroxyacyl-CoA dehydrogenase activity (GO:0016509)

subject	relation	object
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	RO:0000057	hydron (CHEBI:15378)
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	is_a	3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857)
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	RO:0000057	long-chain 3-oxo-fatty acyl-CoA(4-) (CHEBI:136758)
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	RO:0000057	long-chain (3S)-hydroxy fatty acyl-CoA(4-) (CHEBI:136757)
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	RO:0000057	NADH(2-) (CHEBI:57945)

This term has no children.

EC: 1.1.1.211
MetaCyc: 1.1.1.211-RXN
RHEA: 52656