AmiGO 2: Term Details for "core-binding factor complex" (GO:0016513)

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Term Information

Accession: GO:0016513
Name: core-binding factor complex
Ontology: cellular_component
Synonyms: CBF complex, AML1 complex, PEPB2 complex
Alternate IDs: None
Definition: A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit. Source: PMID:8497254, PMID:15156179
Comment: None
History: See term history for GO:0016513 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to core-binding factor complex (excluding "regulates").; Link to all direct and indirect annotations to core-binding factor complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for core-binding factor complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
GO:0008150 biological_process
UBERON:0001062 anatomical entity
GO:0065007 biological regulation
GO:0044237 cellular metabolic process
GO:0009987 cellular process
CARO:0000006 material anatomical entity
GO:0008152 metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0044249 cellular biosynthetic process
GO:0034641 cellular nitrogen compound metabolic process
CARO:0000003 connected anatomical structure
GO:0046483 heterocycle metabolic process
GO:0043170 macromolecule metabolic process
UBERON:0000465 material anatomical entity
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
UBERON:0000061 anatomical structure
GO:0019438 aromatic compound biosynthetic process
GO:0005575 cellular_component
GO:0018130 heterocycle biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0009059 macromolecule biosynthetic process
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0043226 organelle
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0043228 non-membrane-bounded organelle
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0043232 intracellular non-membrane-bounded organelle
GO:0043227 membrane-bounded organelle
GO:0032991 protein-containing complex
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0005694 chromosome
GO:0043231 intracellular membrane-bounded organelle
GO:0003674 molecular_function
PR:000050567 protein-containing material entity
GO:0032993 protein-DNA complex
GO:0006355 regulation of DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0140110 transcription regulator activity
GO:0000785 chromatin
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0140513 nuclear protein-containing complex
GO:0005667 transcription regulator complex
GO:0090575 RNA polymerase II transcription regulator complex
GO:0016513 core-binding factor complex

Parents of core-binding factor complex (GO:0016513)

subject	relation	object
core-binding factor complex	is_a	RNA polymerase II transcription regulator complex (GO:0090575)

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None.