AmiGO 2: Term Details for "NuRD complex" (GO:0016581)

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Term Information

Accession: GO:0016581
Name: NuRD complex
Ontology: cellular_component
Synonyms: NRD complex, nucleosome remodeling and histone deacetylation complex, Mi-2 complex
Alternate IDs: None
Definition: An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. Source: PMID:10589671, PMID:11743021, PMID:17289569
Comment: None
History: See term history for GO:0016581 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to NuRD complex (excluding "regulates").; Link to all direct and indirect annotations to NuRD complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NuRD complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
GO:0016787 hydrolase activity
UBERON:0000061 anatomical structure
CARO:0030000 biological entity
GO:0016043 cellular component organization
GO:0016817 hydrolase activity, acting on acid anhydrides
CARO:0000000 anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0043226 organelle
GO:0043933 protein-containing complex organization
UBERON:0001062 anatomical entity
GO:0003824 catalytic activity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0003674 molecular_function
GO:0043228 non-membrane-bounded organelle
GO:0071824 protein-DNA complex organization
GO:0016462 pyrophosphatase activity
GO:0140657 ATP-dependent activity
GO:0006325 chromatin organization
CARO:0000003 connected anatomical structure
GO:0043232 intracellular non-membrane-bounded organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0043233 organelle lumen
GO:0032991 protein-containing complex
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0016887 ATP hydrolysis activity
GO:0140096 catalytic activity, acting on a protein
GO:1902494 catalytic complex
GO:0005575 cellular_component
GO:0006338 chromatin remodeling
GO:0005694 chromosome
GO:0019213 deacetylase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0005634 nucleus
GO:0032993 protein-DNA complex
GO:1904949 ATPase complex
GO:0000785 chromatin
GO:0140993 histone modifying activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0031981 nuclear lumen
GO:0140513 nuclear protein-containing complex
GO:0033558 protein lysine deacetylase activity
PR:000050567 protein-containing material entity
GO:0004407 histone deacetylase activity
GO:0005654 nucleoplasm
GO:0070603 SWI/SNF superfamily-type complex
GO:0140110 transcription regulator activity
GO:0090545 CHD-type complex
GO:0000118 histone deacetylase complex
GO:0005667 transcription regulator complex
GO:0016581 NuRD complex
GO:0070824 SHREC complex

Parents of NuRD complex (GO:0016581)

subject	relation	object
NuRD complex	is_a	transcription regulator complex (GO:0005667)
NuRD complex	is_a	CHD-type complex (GO:0090545)
NuRD complex	is_a	histone deacetylase complex (GO:0000118)

Children of NuRD complex (GO:0016581)

subject	relation	object
NuRD complex binding (GO:0120325)	RO:0004009	NuRD complex
SHREC complex (GO:0070824)	is_a	NuRD complex

NuRD complex