AmiGO 2: Term Details for "RNA polymerase II, holoenzyme" (GO:0016591)

Term Information

Accession: GO:0016591
Name: RNA polymerase II, holoenzyme
Ontology: cellular_component
Synonyms: DNA-directed RNA polymerase II, holoenzyme
Alternate IDs: None
Definition: A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters. Source: GOC:krc, Wikipedia:Rna_polymerase_ii, GOC:jl, PMID:16858867
Comment: None
History: See term history for GO:0016591 at QuickGO
Chem. react.: None
Subset: goslim_pir
Related: Link to all genes and gene products annotated to RNA polymerase II, holoenzyme (excluding "regulates").; Link to all direct and indirect annotations to RNA polymerase II, holoenzyme (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA polymerase II, holoenzyme (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0003824 catalytic activity
GO:0044237 cellular metabolic process
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
UBERON:0000061 anatomical structure
CARO:0030000 biological entity
GO:0009058 biosynthetic process
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0006725 cellular aromatic compound metabolic process
GO:0044249 cellular biosynthetic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0032991 protein-containing complex
GO:0016772 transferase activity, transferring phosphorus-containing groups
CARO:0000000 anatomical entity
GO:0019438 aromatic compound biosynthetic process
GO:0140098 catalytic activity, acting on RNA
GO:1902494 catalytic complex
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0018130 heterocycle biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:0016779 nucleotidyltransferase activity
GO:0043226 organelle
GO:1901362 organic cyclic compound biosynthetic process
GO:0016740 transferase activity
UBERON:0001062 anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0009059 macromolecule biosynthetic process
CARO:0000006 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0016070 RNA metabolic process
GO:0097747 RNA polymerase activity
GO:1990234 transferase complex
GO:0034062 5'-3' RNA polymerase activity
GO:0005575 cellular_component
CARO:0000003 connected anatomical structure
GO:0043231 intracellular membrane-bounded organelle
GO:0140535 intracellular protein-containing complex
UBERON:0000465 material anatomical entity
GO:0043233 organelle lumen
PR:000050567 protein-containing material entity
GO:0032774 RNA biosynthetic process
GO:0061695 transferase complex, transferring phosphorus-containing groups
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0070013 intracellular organelle lumen
GO:0005634 nucleus
GO:0030880 RNA polymerase complex
GO:0000428 DNA-directed RNA polymerase complex
GO:0031981 nuclear lumen
GO:0140513 nuclear protein-containing complex
GO:0055029 nuclear DNA-directed RNA polymerase complex
GO:0005654 nucleoplasm
GO:0016591 RNA polymerase II, holoenzyme
GO:0016593 Cdc73/Paf1 complex
GO:0005665 RNA polymerase II, core complex
GO:0005672 transcription factor TFIIA complex
GO:0005669 transcription factor TFIID complex
GO:0005673 transcription factor TFIIE complex
GO:0005674 transcription factor TFIIF complex
GO:0005675 transcription factor TFIIH holo complex
GO:0033276 transcription factor TFTC complex

Parents of RNA polymerase II, holoenzyme (GO:0016591)

subject	relation	object
RNA polymerase II, holoenzyme	BFO:0000050	nucleoplasm (GO:0005654)
RNA polymerase II, holoenzyme	is_a	nuclear DNA-directed RNA polymerase complex (GO:0055029)

Children of RNA polymerase II, holoenzyme (GO:0016591)

subject	relation	object
transcription factor TFTC complex (GO:0033276)	BFO:0000050	RNA polymerase II, holoenzyme
transcription factor TFIIH holo complex (GO:0005675)	BFO:0000050	RNA polymerase II, holoenzyme
RNA polymerase II, core complex (GO:0005665)	BFO:0000050	RNA polymerase II, holoenzyme
transcription factor TFIID complex (GO:0005669)	BFO:0000050	RNA polymerase II, holoenzyme
transcription factor TFIIF complex (GO:0005674)	BFO:0000050	RNA polymerase II, holoenzyme
transcription factor TFIIA complex (GO:0005672)	BFO:0000050	RNA polymerase II, holoenzyme
Cdc73/Paf1 complex (GO:0016593)	BFO:0000050	RNA polymerase II, holoenzyme
transcription factor TFIIE complex (GO:0005673)	BFO:0000050	RNA polymerase II, holoenzyme

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