Term Information

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Accession
GO:0016603
Name
glutaminyl-peptide cyclotransferase activity
Ontology
molecular_function
Synonyms
L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing), glutaminyl cyclase activity, glutaminyl-transfer ribonucleate cyclotransferase activity, glutaminyl-tRNA cyclotransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4+. Source: RHEA:23652
Comment
None
History
See term history for GO:0016603 at QuickGO
Chem. react.
has participant N-terminal 5-oxo-L-proline residue
has participant ammonium
has participant L-glutaminiumyl group
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of glutaminyl-peptide cyclotransferase activity (GO:0016603)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glutaminyl-peptide cyclotransferase activity [RO:0000057 relation] RO:0000057  N-terminal 5-oxo-L-proline residue (CHEBI:87215)
glutaminyl-peptide cyclotransferase activity [is_a relation] is_a  catalytic activity, acting on a protein (GO:0140096)
glutaminyl-peptide cyclotransferase activity [RO:0000057 relation] RO:0000057  ammonium (CHEBI:28938)
glutaminyl-peptide cyclotransferase activity [is_a relation] is_a  aminoacyltransferase activity (GO:0016755)
glutaminyl-peptide cyclotransferase activity [RO:0000057 relation] RO:0000057  L-glutaminiumyl group (CHEBI:64722)

This term has no children.

EC
2.3.2.5
MetaCyc
RXN-19145
RHEA
23652