AmiGO 2: Term Details for "ATP hydrolysis activity" (GO:0016887)

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Term Information

Accession: GO:0016887
Name: ATP hydrolysis activity
Ontology: molecular_function
Synonyms: ATP hydrolase activity, ATP phosphohydrolase activity, adenosine 5'-triphosphatase activity, adenosine triphosphatase activity, adenosinetriphosphatase activity, ATP monophosphatase activity
Alternate IDs: GO:0042623, GO:0004002
Definition: Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. Source: RHEA:13065
Comment: Note that this term is meant to specifically represent the ATPase activity of proteins using ATP as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function.
History: See term history for GO:0016887 at QuickGO
Chem. react.: has participant hydrogenphosphate; has participant hydron; has participant ATP(4-); has participant ADP(3-); has participant water
Subset: None
Related: Link to all genes and gene products annotated to ATP hydrolysis activity (excluding "regulates").; Link to all direct and indirect annotations to ATP hydrolysis activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ATP hydrolysis activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016462 pyrophosphatase activity
GO:0140657 ATP-dependent activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0016887 ATP hydrolysis activity
GO:1904949 ATPase complex

Parents of ATP hydrolysis activity (GO:0016887)

subject	relation	object
ATP hydrolysis activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
ATP hydrolysis activity	BFO:0000050	ATP-dependent activity (GO:0140657)
ATP hydrolysis activity	RO:0000057	hydron (CHEBI:15378)
ATP hydrolysis activity	is_a	ribonucleoside triphosphate phosphatase activity (GO:0017111)
ATP hydrolysis activity	RO:0000057	ATP(4-) (CHEBI:30616)
ATP hydrolysis activity	RO:0000057	ADP(3-) (CHEBI:456216)
ATP hydrolysis activity	RO:0000057	water (CHEBI:15377)

Children of ATP hydrolysis activity (GO:0016887)

subject	relation	object
ATP-dependent activity (GO:0140657)	BFO:0000051	ATP hydrolysis activity
ATPase complex (GO:1904949)	RO:0002215	ATP hydrolysis activity

Reactome: R-HSA-5618093; R-HSA-416985; R-HSA-159101; R-HSA-8868658; R-HSA-917693; R-HSA-9668415; R-HSA-8847638; R-HSA-5694425; R-HSA-5654989; R-HSA-3371422; R-HSA-9706399; R-HSA-8939203; R-HSA-9038161; R-HSA-6814678; R-HSA-6811422; R-HSA-6809015; R-HSA-9749350; R-HSA-6814670; R-HSA-6814683; R-HSA-9609860
RHEA: 13065