AmiGO 2: Term Details for "sigma factor activity" (GO:0016987)

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Term Information

Accession: GO:0016987
Name: sigma factor activity
Ontology: molecular_function
Synonyms: DNA-dependent RNA polymerase promoter selection factor, core DNA-dependent RNA polymerase binding promoter specificity activity, sigma transcription factor, bacterial sigma factor activity, plastid sigma factor activity, promoter selection factor activity
Alternate IDs: GO:0000996, GO:0001053
Definition: Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. Source: GOC:txnOH-2018
Comment: None
History: See term history for GO:0016987 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to sigma factor activity (excluding "regulates").; Link to all direct and indirect annotations to sigma factor activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for sigma factor activity (excluding "regulates").

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0080090 regulation of primary metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0003674 molecular_function
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0140110 transcription regulator activity
GO:0003700 DNA-binding transcription factor activity
GO:2000142 regulation of DNA-templated transcription initiation
GO:0016987 sigma factor activity

Parents of sigma factor activity (GO:0016987)

subject	relation	object
sigma factor activity	BFO:0000050	regulation of DNA-templated transcription initiation (GO:2000142)
sigma factor activity	BFO:0000051	core promoter sequence-specific DNA binding (GO:0001046)
sigma factor activity	BFO:0000051	RNA polymerase core enzyme binding (GO:0043175)
sigma factor activity	is_a	DNA-binding transcription factor activity (GO:0003700)

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