AmiGO 2: Term Details for "lipoate synthase activity" (GO:0016992)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0016992
Name: lipoate synthase activity
Ontology: molecular_function
Synonyms: lipoic acid synthase, LS, LipA, lipoyl synthase activity, protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity, protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity
Alternate IDs: GO:0017140
Definition: Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl. Source: EC:2.8.1.8, PMID:18307109
Comment: None
History: See term history for GO:0016992 at QuickGO
Chem. react.: has participant di-mu-sulfido-diiron(1+); has participant S-adenosyl-L-methionine zwitterion; has participant hydron; has participant iron(3+); has participant N(6)-octanoyl-L-lysine residue; has participant hydrosulfide; has participant N(6)-[(R)-dihydrolipoyl]-L-lysine residue; has participant tetra-mu3-sulfido-tetrairon(2+); has participant L-methionine zwitterion; has participant di-mu-sulfido-diiron(2+); has participant 5'-deoxyadenosine
Subset: None
Related: Link to all genes and gene products annotated to lipoate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to lipoate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for lipoate synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0006082 organic acid metabolic process
GO:0071704 organic substance metabolic process
GO:0044281 small molecule metabolic process
GO:0008150 biological_process
GO:0044249 cellular biosynthetic process
GO:1901576 organic substance biosynthetic process
GO:0043436 oxoacid metabolic process
GO:0044283 small molecule biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0009987 cellular process
GO:0006629 lipid metabolic process
GO:0003674 molecular_function
GO:0016053 organic acid biosynthetic process
GO:0044238 primary metabolic process
GO:0046394 carboxylic acid biosynthetic process
GO:0003824 catalytic activity
GO:0044255 cellular lipid metabolic process
GO:0032787 monocarboxylic acid metabolic process
GO:0006631 fatty acid metabolic process
GO:0008610 lipid biosynthetic process
GO:0072330 monocarboxylic acid biosynthetic process
GO:1901360 organic cyclic compound metabolic process
GO:0006790 sulfur compound metabolic process
GO:0016740 transferase activity
GO:0006633 fatty acid biosynthetic process
GO:0009106 lipoate metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0044272 sulfur compound biosynthetic process
GO:0016782 transferase activity, transferring sulphur-containing groups
GO:0009107 lipoate biosynthetic process
GO:0016783 sulfurtransferase activity
GO:0016992 lipoate synthase activity

Parents of lipoate synthase activity (GO:0016992)

subject	relation	object
lipoate synthase activity	RO:0000057	di-mu-sulfido-diiron(1+) (CHEBI:33738)
lipoate synthase activity	RO:0000057	S-adenosyl-L-methionine zwitterion (CHEBI:59789)
lipoate synthase activity	RO:0000057	hydron (CHEBI:15378)
lipoate synthase activity	RO:0000057	iron(3+) (CHEBI:29034)
lipoate synthase activity	RO:0000057	N(6)-octanoyl-L-lysine residue (CHEBI:78809)
lipoate synthase activity	is_a	sulfurtransferase activity (GO:0016783)
lipoate synthase activity	RO:0000057	hydrosulfide (CHEBI:29919)
lipoate synthase activity	RO:0000057	N(6)-[(R)-dihydrolipoyl]-L-lysine residue (CHEBI:83100)
lipoate synthase activity	RO:0000057	tetra-mu3-sulfido-tetrairon(2+) (CHEBI:33722)
lipoate synthase activity	RO:0000057	L-methionine zwitterion (CHEBI:57844)
lipoate synthase activity	BFO:0000050	lipoate biosynthetic process (GO:0009107)
lipoate synthase activity	RO:0000057	di-mu-sulfido-diiron(2+) (CHEBI:33737)
lipoate synthase activity	RO:0000057	5'-deoxyadenosine (CHEBI:17319)

This term has no children.

EC: 2.8.1.8
MetaCyc: RXN0-949; RXN-14950; RXN-14957; RXN-14959
Reactome: R-HSA-6793591
RHEA: 16585