AmiGO 2: Term Details for "N-acylsphingosine amidohydrolase activity" (GO:0017040)

Accession: GO:0017040
Name: N-acylsphingosine amidohydrolase activity
Ontology: molecular_function
Synonyms: acylsphingosine deacylase activity, glycosphingolipid ceramide deacylase
Alternate IDs: None
Definition: Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine. Source: EC:3.5.1.23
Comment: None
History: See term history for GO:0017040 at QuickGO
Chem. react.: has participant sphingosine(1+); has participant N-acylsphingosine; has participant water; has participant fatty acid anion
Subset: None
Related: Link to all genes and gene products annotated to N-acylsphingosine amidohydrolase activity (excluding "regulates").; Link to all direct and indirect annotations to N-acylsphingosine amidohydrolase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for N-acylsphingosine amidohydrolase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
N-acylsphingosine amidohydrolase activity	RO:0000057	sphingosine(1+) (CHEBI:57756)
N-acylsphingosine amidohydrolase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
N-acylsphingosine amidohydrolase activity	RO:0000057	N-acylsphingosine (CHEBI:52639)
N-acylsphingosine amidohydrolase activity	RO:0000057	water (CHEBI:15377)
N-acylsphingosine amidohydrolase activity	RO:0000057	fatty acid anion (CHEBI:28868)

subject	relation	object
phytoceramidase activity (GO:0070774)	is_a	N-acylsphingosine amidohydrolase activity
dihydroceramidase activity (GO:0071633)	is_a	N-acylsphingosine amidohydrolase activity