AmiGO 2: Term Details for "negative cofactor 2 complex" (GO:0017054)

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Term Information

Accession: GO:0017054
Name: negative cofactor 2 complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini. Source: PMID:15574413
Comment: None
History: See term history for GO:0017054 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to negative cofactor 2 complex (excluding "regulates").; Link to all direct and indirect annotations to negative cofactor 2 complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for negative cofactor 2 complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
GO:0008150 biological_process
CARO:0000000 anatomical entity
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
UBERON:0001062 anatomical entity
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
CARO:0000006 material anatomical entity
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0006725 cellular aromatic compound metabolic process
GO:0044249 cellular biosynthetic process
GO:0034641 cellular nitrogen compound metabolic process
CARO:0000003 connected anatomical structure
GO:0046483 heterocycle metabolic process
GO:0043170 macromolecule metabolic process
UBERON:0000465 material anatomical entity
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
UBERON:0000061 anatomical structure
GO:0019438 aromatic compound biosynthetic process
GO:0005575 cellular_component
GO:0018130 heterocycle biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:0051172 negative regulation of nitrogen compound metabolic process
GO:0090304 nucleic acid metabolic process
GO:0043226 organelle
GO:1901362 organic cyclic compound biosynthetic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0010467 gene expression
GO:0043229 intracellular organelle
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0045934 negative regulation of nucleobase-containing compound metabolic process
GO:0043228 non-membrane-bounded organelle
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0005622 intracellular anatomical structure
GO:0043232 intracellular non-membrane-bounded organelle
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0051253 negative regulation of RNA metabolic process
GO:0032991 protein-containing complex
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0005694 chromosome
GO:0043227 membrane-bounded organelle
GO:0003674 molecular_function
GO:1902679 negative regulation of RNA biosynthetic process
GO:0032993 protein-DNA complex
GO:0006355 regulation of DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0140110 transcription regulator activity
GO:0000785 chromatin
GO:0003700 DNA-binding transcription factor activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045892 negative regulation of DNA-templated transcription
PR:000050567 protein-containing material entity
GO:0006357 regulation of transcription by RNA polymerase II
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 DNA-binding transcription repressor activity
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0140513 nuclear protein-containing complex
GO:0017053 transcription repressor complex
GO:0090571 RNA polymerase II transcription repressor complex
GO:0017054 negative cofactor 2 complex

Parents of negative cofactor 2 complex (GO:0017054)

subject	relation	object
negative cofactor 2 complex	is_a	RNA polymerase II transcription repressor complex (GO:0090571)

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None.