AmiGO 2: Term Details for "oxidative phosphorylation uncoupler activity" (GO:0017077)

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Term Information

Accession: GO:0017077
Name: oxidative phosphorylation uncoupler activity
Ontology: molecular_function
Synonyms: mitochondrial uncoupling protein activity, uncoupling protein activity
Alternate IDs: GO:0015302
Definition: Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. Source: PMID:16179945, PMID:15738989
Comment: None
History: See term history for GO:0017077 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to oxidative phosphorylation uncoupler activity (excluding "regulates").; Link to all direct and indirect annotations to oxidative phosphorylation uncoupler activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for oxidative phosphorylation uncoupler activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0006810 transport
GO:0051234 establishment of localization
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0009987 cellular process
GO:0098660 inorganic ion transmembrane transport
GO:0003674 molecular_function
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0098662 inorganic cation transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
GO:0005215 transporter activity
GO:1902600 proton transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0017077 oxidative phosphorylation uncoupler activity
GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity
GO:2000275 regulation of oxidative phosphorylation uncoupler activity

Parents of oxidative phosphorylation uncoupler activity (GO:0017077)

subject	relation	object
oxidative phosphorylation uncoupler activity	is_a	transmembrane transporter activity (GO:0022857)
oxidative phosphorylation uncoupler activity	BFO:0000050	proton transmembrane transport (GO:1902600)

Children of oxidative phosphorylation uncoupler activity (GO:0017077)

subject	relation	object
positive regulation of oxidative phosphorylation uncoupler activity (GO:2000277)	RO:0002213	oxidative phosphorylation uncoupler activity
regulation of oxidative phosphorylation uncoupler activity (GO:2000275)	RO:0002211	oxidative phosphorylation uncoupler activity
negative regulation of oxidative phosphorylation uncoupler activity (GO:2000276)	RO:0002212	oxidative phosphorylation uncoupler activity

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