Term Information

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Accession
GO:0017099
Name
very-long-chain fatty acyl-CoA dehydrogenase activity
Ontology
molecular_function
Synonyms
very long-chain-acyl-CoA dehydrogenase activity, very-long-chain acyl-CoA dehydrogenase activity
Alternate IDs
None
Definition
Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. Source: RHEA:19181
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History
See term history for GO:0017099 at QuickGO
Chem. react.
has participant very long-chain 2,3-trans-enoyl CoA(4-)
has participant very long-chain 3-substituted propanoyl-CoA(4-)
has participant hydron
has participant FAD(3-)
has participant FADH2(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of very-long-chain fatty acyl-CoA dehydrogenase activity (GO:0017099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
very-long-chain fatty acyl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  very long-chain 2,3-trans-enoyl CoA(4-) (CHEBI:83728)
very-long-chain fatty acyl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  very long-chain 3-substituted propanoyl-CoA(4-) (CHEBI:83724)
very-long-chain fatty acyl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
very-long-chain fatty acyl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  FAD(3-) (CHEBI:57692)
very-long-chain fatty acyl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  FADH2(2-) (CHEBI:58307)
very-long-chain fatty acyl-CoA dehydrogenase activity [is_a relation] is_a  acyl-CoA dehydrogenase activity (GO:0003995)

This term has no children.

EC
1.3.8.9
Reactome
R-HSA-548831
RHEA
19181