AmiGO 2: Term Details for "aminoacyl-tRNA synthetase multienzyme complex" (GO:0017101)

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Term Information

Accession: GO:0017101
Name: aminoacyl-tRNA synthetase multienzyme complex
Ontology: cellular_component
Synonyms: aminoacyl-tRNA synthetase complex, multisynthetase complex
Alternate IDs: None
Definition: A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates. Source: PMID:16169847, GOC:jl
Comment: None
History: See term history for GO:0017101 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to aminoacyl-tRNA synthetase multienzyme complex (excluding "regulates").; Link to all direct and indirect annotations to aminoacyl-tRNA synthetase multienzyme complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for aminoacyl-tRNA synthetase multienzyme complex (excluding "regulates").

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GO:0005575 cellular_component
GO:0003674 molecular_function
PR:000050567 protein-containing material entity
GO:0003824 catalytic activity
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0140535 intracellular protein-containing complex
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex

Parents of aminoacyl-tRNA synthetase multienzyme complex (GO:0017101)

subject	relation	object
aminoacyl-tRNA synthetase multienzyme complex	is_a	intracellular protein-containing complex (GO:0140535)
aminoacyl-tRNA synthetase multienzyme complex	is_a	catalytic complex (GO:1902494)

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