Term Information

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Accession
GO:0017136
Name
NAD-dependent histone deacetylase activity
Ontology
molecular_function
Synonyms
SIR2
Alternate IDs
None
Definition
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone. Source: PMID:28450737
Comment
None
History
See term history for GO:0017136 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0017136 from QuickGO

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Parents of NAD-dependent histone deacetylase activity (GO:0017136)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NAD-dependent histone deacetylase activity [is_a relation] is_a  histone deacetylase activity (GO:0004407)
NAD-dependent histone deacetylase activity [is_a relation] is_a  NAD-dependent protein deacetylase activity (GO:0034979)
Children of NAD-dependent histone deacetylase activity (GO:0017136)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NAD-dependent histone H3K56 deacetylase activity (GO:0140765) [is_a relation] is_a  NAD-dependent histone deacetylase activity
NAD-dependent histone H3K14 deacetylase activity (GO:0032041) [is_a relation] is_a  NAD-dependent histone deacetylase activity
NAD-dependent histone H4K16 deacetylase activity (GO:0046970) [is_a relation] is_a  NAD-dependent histone deacetylase activity
NAD-dependent histone H3K9 deacetylase activity (GO:0046969) [is_a relation] is_a  NAD-dependent histone deacetylase activity
NAD-dependent histone H3K18 deacetylase activity (GO:0097372) [is_a relation] is_a  NAD-dependent histone deacetylase activity
None.