Term Information

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Accession
GO:0017178
Name
diphthine-ammonia ligase activity
Ontology
molecular_function
Synonyms
diphthamide synthase activity, diphthamide synthetase activity, diphthine:ammonia ligase (ADP-forming)
Alternate IDs
None
Definition
Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate. Source: EC:6.3.1.14, RHEA:19753
Comment
None
History
See term history for GO:0017178 at QuickGO
Chem. react.
has participant adenosine 5'-monophosphate(2-)
has participant diphthamide residue
has participant hydron
has participant diphthine betaine residue
has participant ammonium
has participant ATP(4-)
has participant diphosphate(3-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of diphthine-ammonia ligase activity (GO:0017178)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
diphthine-ammonia ligase activity [is_a relation] is_a  acid-ammonia (or amide) ligase activity (GO:0016880)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  diphthamide residue (CHEBI:16692)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  diphthine betaine residue (CHEBI:82696)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  ammonium (CHEBI:28938)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
diphthine-ammonia ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)

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EC
6.3.1.14
KEGG_REACTION
R03613
MetaCyc
DIPHTINE--AMMONIA-LIGASE-RXN
Reactome
R-HSA-5358475
RHEA
19753