AmiGO 2: Term Details for "vanillate monooxygenase activity" (GO:0018489)

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Term Information

Accession: GO:0018489
Name: vanillate monooxygenase activity
Ontology: molecular_function
Synonyms: vanillate demethylase (aerobic) activity, vanillate demethylase activity, 4-hydroxy-3-methoxybenzoate demethylase activity, vanillate:oxygen oxidoreductase (demethylating)
Alternate IDs: None
Definition: Catalysis of the reaction: H+ + NADH + O2 + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD+. Source: RHEA:13021, EC:1.14.13.82
Comment: Note that this was EC:1.2.3.12.
History: See term history for GO:0018489 at QuickGO
Chem. react.: has participant water; has participant formaldehyde; has participant vanillate; has participant hydron; has participant 3,4-dihydroxybenzoate; has participant NAD(1-); has participant NADH(2-); has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to vanillate monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to vanillate monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for vanillate monooxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016491 oxidoreductase activity
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0032451 demethylase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0018489 vanillate monooxygenase activity

Parents of vanillate monooxygenase activity (GO:0018489)

subject	relation	object
vanillate monooxygenase activity	RO:0000057	water (CHEBI:15377)
vanillate monooxygenase activity	RO:0000057	formaldehyde (CHEBI:16842)
vanillate monooxygenase activity	is_a	demethylase activity (GO:0032451)
vanillate monooxygenase activity	RO:0000057	vanillate (CHEBI:16632)
vanillate monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)
vanillate monooxygenase activity	RO:0000057	hydron (CHEBI:15378)
vanillate monooxygenase activity	RO:0000057	3,4-dihydroxybenzoate (CHEBI:36241)
vanillate monooxygenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
vanillate monooxygenase activity	RO:0000057	NADH(2-) (CHEBI:57945)
vanillate monooxygenase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.

EC: 1.14.13.82
KEGG_REACTION: R05274
MetaCyc: RXN-2; RXN-10891
RHEA: 13021
UM-BBD_reactionID: r0146