AmiGO 2: Term Details for "phthalate 4,5-dioxygenase activity" (GO:0018620)

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Term Information

Accession: GO:0018620
Name: phthalate 4,5-dioxygenase activity
Ontology: molecular_function
Synonyms: PDO activity, phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating), phthalate dioxygenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: H+ + NADH + O2 + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+. Source: EC:1.14.12.7, RHEA:17489
Comment: None
History: See term history for GO:0018620 at QuickGO
Chem. react.: has participant phthalate(2-); has participant NAD(1-); has participant hydron; has participant dioxygen; has participant cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate(2-); has participant NADH(2-)
Subset: None
Related: Link to all genes and gene products annotated to phthalate 4,5-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to phthalate 4,5-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phthalate 4,5-dioxygenase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0051213 dioxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
GO:0018620 phthalate 4,5-dioxygenase activity

Parents of phthalate 4,5-dioxygenase activity (GO:0018620)

subject	relation	object
phthalate 4,5-dioxygenase activity	RO:0000057	phthalate(2-) (CHEBI:17563)
phthalate 4,5-dioxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor (GO:0016708)
phthalate 4,5-dioxygenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
phthalate 4,5-dioxygenase activity	RO:0000057	hydron (CHEBI:15378)
phthalate 4,5-dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
phthalate 4,5-dioxygenase activity	RO:0000057	cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate(2-) (CHEBI:58237)
phthalate 4,5-dioxygenase activity	RO:0000057	NADH(2-) (CHEBI:57945)

This term has no children.

EC: 1.14.12.7
KEGG_REACTION: R03630
MetaCyc: PHTHALATE-45-DIOXYGENASE-RXN
RHEA: 17489
UM-BBD_reactionID: r0102