AmiGO 2: Term Details for "SCF ubiquitin ligase complex" (GO:0019005)

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Term Information

Accession: GO:0019005
Name: SCF ubiquitin ligase complex
Ontology: cellular_component
Synonyms: CDL1 complex, CRL1 complex, Cul1-RING ubiquitin ligase complex, SCF complex, Skp1/Cul1/F-box protein complex, cullin-RING ligase 1, SCF complex substrate recognition subunit
Alternate IDs: None
Definition: A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Source: PMID:15688063, PMID:15571813
Comment: None
History: See term history for GO:0019005 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to SCF ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations to SCF ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for SCF ubiquitin ligase complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0003824 catalytic activity
GO:0016755 aminoacyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0003674 molecular_function
GO:0005575 cellular_component
GO:0032991 protein-containing complex
PR:000050567 protein-containing material entity
GO:0019787 ubiquitin-like protein transferase activity
GO:1902494 catalytic complex
GO:0061659 ubiquitin-like protein ligase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0140535 intracellular protein-containing complex
GO:1990234 transferase complex
GO:0061630 ubiquitin protein ligase activity
GO:0000151 ubiquitin ligase complex
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0019005 SCF ubiquitin ligase complex
GO:0043223 cytoplasmic SCF ubiquitin ligase complex
GO:0043224 nuclear SCF ubiquitin ligase complex
GO:0097660 SCF-Cdc4 ubiquitin ligase complex
GO:0097661 SCF-Ctf13 ubiquitin ligase complex
GO:0097662 SCF-Das1 ubiquitin ligase complex
GO:0097663 SCF-Dia2/Pof3 ubiquitin ligase complex
GO:0097664 SCF-Grr1/Pof2 ubiquitin ligase complex
GO:0097675 SCF-Hrt3/Pof7 ubiquitin ligase complex
GO:0097665 SCF-Mdm30 ubiquitin ligase complex
GO:0097666 SCF-Met30/Pof1 ubiquitin ligase complex
GO:0097672 SCF-Pof5 ubiquitin ligase complex
GO:0097667 SCF-Rcy1/Pof6 ubiquitin ligase complex
GO:0097668 SCF-Saf1/Pof9 ubiquitin ligase complex
GO:0097669 SCF-Skp2 ubiquitin ligase complex
GO:0097673 SCF-Ucc1 ubiquitin ligase complex
GO:0097670 SCF-Ufo1/Pof10 ubiquitin ligase complex
GO:0097671 SCF-YDR131C ubiquitin ligase complex
GO:0097674 SCF-YLR352W ubiquitin ligase complex

Parents of SCF ubiquitin ligase complex (GO:0019005)

subject	relation	object
SCF ubiquitin ligase complex	is_a	cullin-RING ubiquitin ligase complex (GO:0031461)

Children of SCF ubiquitin ligase complex (GO:0019005)

subject	relation	object
SCF-Das1 ubiquitin ligase complex (GO:0097662)	is_a	SCF ubiquitin ligase complex
nuclear SCF ubiquitin ligase complex (GO:0043224)	is_a	SCF ubiquitin ligase complex
SCF-Hrt3/Pof7 ubiquitin ligase complex (GO:0097675)	is_a	SCF ubiquitin ligase complex
SCF-Rcy1/Pof6 ubiquitin ligase complex (GO:0097667)	is_a	SCF ubiquitin ligase complex
SCF-YDR131C ubiquitin ligase complex (GO:0097671)	is_a	SCF ubiquitin ligase complex
SCF-Met30/Pof1 ubiquitin ligase complex (GO:0097666)	is_a	SCF ubiquitin ligase complex
SCF-Pof5 ubiquitin ligase complex (GO:0097672)	is_a	SCF ubiquitin ligase complex
SCF-Cdc4 ubiquitin ligase complex (GO:0097660)	is_a	SCF ubiquitin ligase complex
SCF complex disassembly in response to cadmium stress (GO:1990171)	RO:0002590	SCF ubiquitin ligase complex
SCF-YLR352W ubiquitin ligase complex (GO:0097674)	is_a	SCF ubiquitin ligase complex
SCF ubiquitin ligase complex binding (GO:1905761)	RO:0004009	SCF ubiquitin ligase complex
SCF-Grr1/Pof2 ubiquitin ligase complex (GO:0097664)	is_a	SCF ubiquitin ligase complex
SCF-Saf1/Pof9 ubiquitin ligase complex (GO:0097668)	is_a	SCF ubiquitin ligase complex
SCF-Dia2/Pof3 ubiquitin ligase complex (GO:0097663)	is_a	SCF ubiquitin ligase complex
SCF-Ctf13 ubiquitin ligase complex (GO:0097661)	is_a	SCF ubiquitin ligase complex
SCF complex assembly (GO:0010265)	RO:0002588	SCF ubiquitin ligase complex
SCF-Mdm30 ubiquitin ligase complex (GO:0097665)	is_a	SCF ubiquitin ligase complex
SCF-Skp2 ubiquitin ligase complex (GO:0097669)	is_a	SCF ubiquitin ligase complex
SCF-Ucc1 ubiquitin ligase complex (GO:0097673)	is_a	SCF ubiquitin ligase complex
SCF-Ufo1/Pof10 ubiquitin ligase complex (GO:0097670)	is_a	SCF ubiquitin ligase complex
cytoplasmic SCF ubiquitin ligase complex (GO:0043223)	is_a	SCF ubiquitin ligase complex

Wikipedia: SCF_complex