AmiGO 2: Term Details for "DNA N-glycosylase activity" (GO:0019104)

Accession: GO:0019104
Name: DNA N-glycosylase activity
Ontology: molecular_function
Synonyms: DNA glycosylase activity, endonuclease VIII activity
Alternate IDs: GO:0008578
Definition: Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. Source: PMID:11554296, GOC:elh
Comment: None
History: See term history for GO:0019104 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA N-glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations to DNA N-glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA N-glycosylase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
DNA N-glycosylase activity	is_a	hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
DNA N-glycosylase activity	is_a	catalytic activity, acting on DNA (GO:0140097)

subject	relation	object
mismatch base pair DNA N-glycosylase activity (GO:0000700)	is_a	DNA N-glycosylase activity
oxidized base lesion DNA N-glycosylase activity (GO:0000702)	is_a	DNA N-glycosylase activity
pyrimidine dimer DNA N-glycosylase activity (GO:0000704)	is_a	DNA N-glycosylase activity
deaminated base DNA N-glycosylase activity (GO:0097506)	is_a	DNA N-glycosylase activity
alkylbase DNA N-glycosylase activity (GO:0003905)	is_a	DNA N-glycosylase activity

Reactome: R-HSA-5220959; R-HSA-110250; R-HSA-9635996; R-HSA-9636008; R-HSA-5221061; R-HSA-110248; R-HSA-9629497; R-HSA-5649664; R-HSA-110218; R-HSA-9629499; R-HSA-5649658; R-HSA-9629216; R-HSA-9629149; R-HSA-110219; R-HSA-110251; R-HSA-9629470; R-HSA-9629492; R-HSA-110232; R-HSA-5649681; R-HSA-110231; R-HSA-9629483; R-HSA-110234; R-HSA-5649673; R-HSA-110246