AmiGO 2: Term Details for "2-hydroxyglutarate synthase activity" (GO:0019142)

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Term Information

Accession: GO:0019142
Name: 2-hydroxyglutarate synthase activity
Ontology: molecular_function
Synonyms: 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity, 2-hydroxyglutaratic synthetase activity, 2-hydroxyglutaric synthetase activity, alpha-hydroxyglutarate synthase activity, hydroxyglutarate synthase activity, propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)
Alternate IDs: None
Definition: Catalysis of the reaction: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H+. Source: RHEA:19185
Comment: Note that this function was formerly EC:4.1.3.9.
History: See term history for GO:0019142 at QuickGO
Chem. react.: has participant coenzyme A(4-); has participant 2-hydroxyglutarate(2-); has participant glyoxylate; has participant propionyl-CoA(4-); has participant hydron; has participant water
Subset: None
Related: Link to all genes and gene products annotated to 2-hydroxyglutarate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to 2-hydroxyglutarate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 2-hydroxyglutarate synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
GO:0019142 2-hydroxyglutarate synthase activity

Parents of 2-hydroxyglutarate synthase activity (GO:0019142)

subject	relation	object
2-hydroxyglutarate synthase activity	RO:0000057	coenzyme A(4-) (CHEBI:57287)
2-hydroxyglutarate synthase activity	RO:0000057	2-hydroxyglutarate(2-) (CHEBI:11596)
2-hydroxyglutarate synthase activity	RO:0000057	glyoxylate (CHEBI:36655)
2-hydroxyglutarate synthase activity	RO:0000057	propionyl-CoA(4-) (CHEBI:57392)
2-hydroxyglutarate synthase activity	RO:0000057	hydron (CHEBI:15378)
2-hydroxyglutarate synthase activity	is_a	acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)
2-hydroxyglutarate synthase activity	RO:0000057	water (CHEBI:15377)

This term has no children.

EC: 2.3.3.11
KEGG_REACTION: R00932
MetaCyc: HYDGLUTSYN-RXN
RHEA: 19185